HESI® A2 Chemistry Practice Test

Prepare for your test with realistic questions.

Free HESI A2 Chemistry Practice Test (updated 2026)

The HESI® A2 Chemistry test covers various chemistry concepts, including atomic structure, equilibrium, stoichiometry, biochemistry, scientific notation, and chemical reactions.

Click “Start Test” above to take a free HESI A2 Chemistry practice test!

What’s on the HESI Chemistry Test?

A section outline for HESI A2 Chemistry showing 30 questions covering topics like scientific notation, metric system, periodic table, chemical reactions, stoichiometry, acids and bases, and biochemistry.

HESI A2 Chemistry Practice Questions

One of the best ways to test your knowledge is by taking a practice test. Evaluate your chemistry knowledge by trying your hand at the three practice questions below!

Answer each question and read through the answer explanation, whether you got the answer right or wrong. This will help you ensure you’ve got the topic mastered.

Whether you struggled with these questions or aced them on your first try, be sure to take the full practice test to get a better idea of how prepared you really are!

1. Which of the following substances allows for the fastest diffusion?


In chemistry, diffusion is defined as the movement of matter from areas of high to low concentration by the random motion of molecules. Particle freedom positively correlates to speed of diffusion.

Diffusion is fastest through gases because the particles move rapidly and have comparatively large amounts of space between them, allowing them to spread out. The next fastest medium for diffusion is liquid, followed by gel (semi-solid), and then solids. There is even some minuscule degree of diffusion in solids, which rises in proportion to the temperature of the substance.
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2. Which of the following could be an empirical formula?


An empirical formula is the smallest expression of a chemical formula. To be empirical, a formula must be incapable of being reduced. For this reason, C4H6, C2H6, and C3H6 are incorrect, as they could all be reduced to a simpler form (C2H3, CH3, and CH2, respectively).

Note that empirical formulas are not the same as molecular formulas, which do not have to be irreducible. Two compounds can have the same empirical formula but different molecular formulas. The molecular formula is a description of the actual number of each atom in the molecule, not just their relative amounts.
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3. How is energy generated in a nuclear reaction?


In a nuclear reaction, be it fission or fusion, matter is converted into energy. Einstein first postulated the law of energy-mass conservation using the equation \(E=mc^2\), where \(m\) is mass, \(E\) is energy and \(c\) is the speed of light. Looking closely at this equation shows that a tiny amount of matter can produce a large amount of energy, which is why nuclear reactions are so energetic.
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HESI A2 Online Prep Course

If you want to be fully prepared, Mometrix offers an online HESI prep course designed to give you everything you need to succeed!

Here’s what you’ll find in the HESI A2 course:

  • 80+ Review Lessons Covering Every Topic
  • Over 3,200 HESI A2 Practice Questions
  • 550+ Digital Flashcards
  • 180+ Instructional Videos
  • Money-back Guarantee
  • Mobile Access

Everyone learns differently, so we’ve tailored the HESI online prep course to ensure every learner has what they need to prepare for the HESI exam.

Click below to check it out!

FAQs

Q

How many questions are on the Chemistry section of the HESI A2?

A

There are 30 questions on the Chemistry section of the HESI A2 exam.

Q

How long is the Chemistry section of the HESI A2?

A

Each school sets their own time limit for each section of the exam.

Q

What is a passing score for the Chemistry section of the HESI A2?

A

There are no official passing scores or failing scores on the HESI exam.

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Edited by Aaron Lanni

Aaron is the content manager and lead editor for Mometrix Academy. He regularly produces, updates, proofreads, and edits content to ensure it meets Mometrix’s quality and accessibility standards.

HESI is a registered trademark of Elsevier, Inc., which was not involved in the production of, and does not endorse, this page.

 

by Mometrix Test Preparation | Last Updated: July 21, 2026