SPEX Practice Test

SPEX is specifically used in the United States and Canada to re-assess physicians and their ability to understand basic medical knowledge. In order to take this exam, the individual must currently hold or have previously held an unlimited license to practice medicine.

This computer-based exam consists of multiple-choice questions. The exam consists of 7 blocks. Each block allows 64 minutes to complete 48 questions. The estimated passing score is 75.

SPEX Study Guide

SPEX Flashcards

If you require special accommodations, this request must be made in writing when the exam application is submitted.


To take SPEX through the board-sponsored process, you must have held a valid, unlimited license, and met eligibility requirements established by the licensing board(s).

To take SPEX as self-nominated, you must currently hold a valid, unlimited license.

What are the topics covered?

The two areas assessed are “General Principles” and “Individual Organ Systems”.

The “General Principles” section covers items that are not limited to certain organ systems. The following subjects are covered in the exam.

General Principles – 1.5%

Individual Organ Systems – 76.5%

  • Immune System
  • Blood and Lymphoreticular System
  • Behavioral Health
  • Nervous System & Special Senses
  • Skin & Subcutaneous Tissue
  • Musculoskeletal System
  • Cardiovascular System
  • Respiratory System
  • Gastrointestinal System
  • Renal & Urinary System
  • Pregnancy, Childbirth, & the Puerperium
  • Female Reproductive System & Breast
  • Male Reproductive System
  • Endocrine System
  • Multisystem Processes & Disorders

Biostatistics & Epidemiology/Population Health & Interpretation of Medical Literature/Social Sciences – 22%

How do I register for the exam?

  • If you have not already done so, you must create an account on the online application system.
  • Submit your application, certification of identity form (if applicable), and fee.
  • Verify you meet all eligibility requirements.

Once your application has been reviewed and approved, you will receive an email. This typically takes 5-7 days.

After you receive approval, you will be emailed a copy of your Scheduling Permit. The permit is used to schedule your exam. Also, you must take the Scheduling Permit with you on exam day in order to take the test.

Check out Mometrix's SPEX Study Guide

Get practice questions, video tutorials, and detailed study lessons

Get Your Study Guide
 Study Guide

What is the cost of the exam?

The cost of SPEX is $1,300. This fee is non-refundable and non-transferable. It must be paid with American Express, MasterCard or Visa.

What are the testing dates and locations?

The Scheduling Permit you receive entitles you to a 90-day eligibility period in which you can take the exam.

Test appointments are made on a first-come, first-served basis.

There are over 300 testing sites throughout the US, Canada, Puerto Rico, and the Virgin Islands.

What should I do the day of the exam?

Bring a valid photo ID and Scheduling Permit.

You are not allowed to bring a calculator to the testing area. Additionally, you are prohibited from bringing personal items such as a jacket, backpack, or cell phone.

What happens after I take the exam?

Your test results will be available 2-4 weeks after you take the exam.

What happens if I don’t pass the exam?

In a 12-month period, you will be given three attempts to take the exam. You are allowed to make a second attempt at the exam at any point after the first attempt. If a third attempt is required, you must wait 90 days from the day of the second attempt. Any attempts at the exam after these three, there is a mandatory one-year waiting period from the first time you took the exam.

Mometrix has developed the study guide you need to pass SPEX. Of course, we don’t give you answers to the questions that will be on SPEX, but we will provide you with practice on the types of questions you will see, which you will find to be a great help.

Throughout the process of studying for this exam, there will be times when you can’t sit at your desk, so you need a tool that will help you on the go. Our flashcards do just that!

SPEX Study Guide

Mometrix Academy is a completely free SPEX exam preparation resource provided by Mometrix Test Preparation. If you find benefit from our SPEX review efforts here, check out our premium quality SPEX study guide to take your studying to the next level. Just click the SPEX Secrets Study Guide link below. Your purchase also helps us make even more great, free SPEX examination content for test-takers.

Check out Mometrix's SPEX Flashcards

Get complex subjects broken down into easily understandable concepts

Get Your Flashcards

Upgrade your studying with our SPEX study guide and flashcards:
SPEX Study Guide
SPEX Flashcards

SPEX Study Guide Customer Success Stories

Our customers love the tutorial videos from Mometrix Academy that we have incorporated into our SPEX study guide. The SPEX study guide reviews below are examples of customer experiences.

book is easy to read and not at all intimidating...making me not feel overwhelmed of the broad topics of coverage of the exam....each topic just gives the most pertinent information about it....level of information coverage was appropriate for the SPEX exam. I appreciated the test taking strategies a lot....thats the skill i wanted to develop more.

SPEX Study Guide – Rachel

Excellent material for learning the topics covered on the exam. Also has review videos for select high-yield topics like cardiology and respiratory disorders.

SPEX Study Guide – Mikael

I am using it for study now. It met my expectations, it is portable, useful and well organized.

SPEX Study Guide – Mia

This study guide has been rated very highly by most of my peer studying for the licensure. It is rated consistently by these successful friends.

SPEX Study Guide – Nene

Material is well organized and easy to locate. Subjects are adequate for a review and as an indicator for needed detail study.

SPEX Study Guide – Customer

I am very impressed with the materials so far. These study aids are very useful for preparation.

SPEX Study Guide – Raj

Since it has been more than a number of years since finishing medical school I am more than a little bit nervous about taking the exam and was looking for something to help that was not overwhelming yet thorough. SPEX secrets is the answer!

SPEX Study Guide – Roberta

This book is an excellent resource. The tips and tricks will give the security to take this test with confidence.In each section the complexed material is broken down in an easy to read format.This is definitely a way to organize your study session.

SPEX Study Guide – Sametra

Mometrix Academy – Home


by Mometrix Test Preparation | This Page Last Updated: January 16, 2023